The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease.
نویسندگان
چکیده
BACKGROUND Parkinson's disease is accompanied by deficits in passive motion and limb position sense. OBJECTIVE To investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits. METHODS AND RESULTS A passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON. CONCLUSIONS STN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery of proprioceptive function.
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ورودعنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 76 4 شماره
صفحات -
تاریخ انتشار 2005